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Molecular Biomechanics
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Proteins are exposed to and tightly regulated by external perturbations, binding partners and mechanical stress, altering their assembly and reactivity. Revealing the molecular driving forces and evolutionary constraints in biomolecular systems is a requirement of designing biological materials and processes, for applications in material science and biomedicine, which is the aim of our research. Our research focuses on protein materials and fibers such as silk, disordered proteins and protein folding, the extra-cellular matrix, enzymes and allosteric proteins. Evolutionary design is a complementary aspect we consider for understanding physiological functions of these systems. We make use and further develop various computational and theoretical techniques, among others molecular modelling, high-performance molecular simulations, finite element analysis and bioinformatics approaches. For virtually all of the projects, we extensively collaborate with experimental research labs.
The new group leader, Frauke Gräter, has joined EML Research on July 15, 2009. She will establish her research group and in doing so create contents for the web site.
For the time being, visit the webpage of her previous affiliation.
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