Übersicht
colloquia - [ 13.11.2006 (11.00) ]
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"From Bare FeO+ to Cytochrome P-450: New Insight in the Intriguing Mechanisms of C-H Bond Oxygenation"
Sprecher: Professor Dr. Helmut Schwarz, Technische Universität Berlin
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Abstract (by author)
A mechanistic scheme for the oxygenation of hydrocarbons is presented based on detailed ion-molecule reactions in the gas phase and electronic structure calculations of binary transition-metal oxides. As a result of this combined experimental/computational approach a new paradigm, called two-state reactivity (TSR), is presented that will be applied to the hydroxylation of alkanes and related processes. It is proposed that in thermal reactions spin-crossing effects can dramatically affect reaction mechanisms, rate constants, branching ratios and temperature behaviour of organometallic transformations. Actually, spin-changes can accelerate and promote otherwise extremely inefficient processes, and based on this concept a novel mechanism pertaining to the catalytic action of P-450 is suggested.
Bibliographisches zu dem Referenten/Referentin finden Sie unter: http://www.chem.tu-berlin.de/helmut.schwarz/
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Ort:
Carl-Bosch-Auditorium des Studios der Villa Bosch, 69118 Heidelberg, Schloss-Wolfsbrunnenweg 33 (Eingang Studio - ca. 100 m vom Eingang zur Villa Bosch entfernt, auf der Talseite des Schloss-Wolfsbrunnenweges; Näheres zur Anfahrt siehe unter www.studio.villa-bosch.de.
Parken:
Tiefgarage „Unter der Boschwiese“ (unentgeltlich).
Contact:
Bärbel Mack
EML Research gGmbH
Schloss-Wolfsbrunnenweg 33
69118 Heidelberg
Phone: +49 (0)6221 - 533 - 201
Fax: +49 (0)6221 - 533 - 298
Email: [email protected]
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