The
aim of this project is to develop and apply computer-aided methods to model, simulate and predict how biomolecules interact. The focus is on the interactions of proteins. The methods make use of three-dimensional macromolecular structures and combine approaches based on physicochemical principles with those of chemo- and bio-informatics - see our database and software websites.
Applications are made to systems of biological or medicinal interest, and include modeling of : -Signal Recognition Particle (SRP) interactions (with Irmi Sinning, University of Heidelberg) -Cysteine Synthase Complexes (with Ruediger Hell and Markus Wirtz, University of Heidelberg) -Ubiquitination proteins and their interactions (with Amit Banerjee, Wayne State University, USA) - see the Ubiquitin and Ubiquitin-like Protein Web Resource.
page last modified: Friday,
13.07.2007
Project Manager
Dr. Rebecca Wade Email:
Phone: +49 (0)6221 - 533 - 247 Fax: +49 (0)6221 - 533 - 298 more >>
