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UniNet is an European research initiative
aiming to identify and investigate common mathematical structures in
various complex networks, such as genetic, metabolic (particularly at
our site), neuronal, ecological and economic ones.
In the consortium we are responsible for metabolic networks. Among
the difficulties in modelling biochemical systems are: the high
number of kinetic parameters involved, most of them unknown a
priori, the large number of reactions in the network, which might make
even the numerical simulations demanding, the multiple
time-scales in the system, leading to stiff equation systems.
In
order to find some solutions to especially the first problem, we
employ Stoichiometric Network Analysis (SNA). Our aim is to find
conditions for stability or instability of the steady states without
explicit knowledge of the kinetic parameters.
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